Which antiseptic solution is most appropriate for hand hygiene in an immunocompromised client?

Chlorhexidine is an appropriate choice for hand hygiene in an immunocompromised client due to its broad-spectrum antimicrobial properties and persistent activity. It is a powerful antiseptic that is effective against a variety of pathogens, including bacteria and fungi. For patients who are immunocompromised, maintaining a sterile environment is critical, as they are more susceptible to infections.

Chlorhexidine not only effectively reduces the microbial load on the skin but also provides lasting antibacterial effects after application, which can be especially beneficial in preventing infections. Unlike some other antiseptics, it does not dry out the skin as readily, which is an important consideration for individuals who may already have compromised skin integrity.

In contrast, while alcohol-based hand sanitizers are effective against many types of germs, they may not provide prolonged protection and can be less effective when hands are visibly soiled. Povidone-iodine is another antiseptic, primarily used for preparing the skin before surgery, but it may not be the best option for routine hand hygiene. Lastly, soap and water are effective for mechanical cleaning and reducing the number of germs but may not offer the same level of antimicrobial action as chlorhexidine in high-risk scenarios.