What is the toxic level for Phenytoin?

Phenytoin, an anticonvulsant used primarily for controlling seizures, must be monitored carefully due to its narrow therapeutic range. The therapeutic levels of phenytoin typically fall between 10 to 20 micrograms per milliliter (mcg/mL). When levels exceed 20 mcg/mL, the risk of toxicity increases significantly.

A level greater than 30 mcg/mL is generally considered toxic. At this level, patients may start experiencing adverse effects such as ataxia, confusion, slurred speech, and lethargy, which can progress to more severe complications if not addressed. Monitoring and managing the dosage of phenytoin is crucial to prevent these toxic effects and ensure patient safety.

Thus, identifying the toxic level at greater than 30 mcg/mL is important for healthcare providers to avoid potential complications associated with phenytoin therapy.