What is the primary issue that atherosclerosis causes in the arteries?

The primary issue that atherosclerosis causes in the arteries is the blockage due to plaque build-up. Atherosclerosis is a condition characterized by the accumulation of fatty deposits, cholesterol, and other substances in the arterial walls, leading to the formation of plaques. Over time, these plaques can grow and protrude into the lumen of the arteries, causing a significant narrowing and potential blockage of blood flow.

This blockage can impede the delivery of oxygen and nutrients to tissues and organs, leading to various cardiovascular complications, such as angina, myocardial infarction (heart attack), or even stroke if blood flow to the brain is affected. The process begins subtly but can have profound effects on overall cardiovascular health as the plaques can become unstable and rupture, further complicating the situation.

While narrowing of arteries, weakening of arterial walls, and loss of elasticity may also be related to the progression of atherosclerosis, the direct and most immediate issue caused by the deposition of plaques is the resulting blockage that disrupts normal blood flow.