What is a contraindication for the use of methylergonovine?

Methylergonovine is a medication that is primarily used to manage postpartum hemorrhage by promoting uterine contraction. However, it has specific contraindications due to its pharmacological effects, particularly related to vascular tone and blood pressure.

Hypertension is a well-established contraindication for the use of methylergonovine. The medication can cause vasoconstriction, leading to elevated blood pressure, which can be dangerous for patients with pre-existing hypertension. In patients who already have high blood pressure, the use of methylergonovine could significantly increase the risk of cardiovascular complications, including stroke or heart attack.

By avoiding the use of methylergonovine in patients with hypertension, healthcare providers can prevent exacerbating their condition and maintain stability in their cardiovascular health. In contrast, while recent stroke, diabetes mellitus, and heart failure may pose risks or require caution in management, they are not outright contraindications for methylergonovine in the same way that hypertension is.