What can be a side effect of administering betamethasone?

Betamethasone is a corticosteroid used to reduce inflammation and suppress the immune system. One of the notable side effects of corticosteroids, including betamethasone, is the increase in blood glucose levels. This can lead to hyperglycemia, especially in individuals with diabetes or those at risk for developing diabetes, resulting in a temporary state of high blood sugar. If the body doesn't manage to control these elevated glucose levels, it might become a significant concern, particularly leading to complications such as diabetic ketoacidosis.

The association of corticosteroids with hyperglycemia explains why hypoglycemia can be an unlikely outcome. In contrast, the body's increased insulin resistance and altered metabolism as a result of corticosteroid therapy would more likely exacerbate blood sugar levels rather than lower them. Therefore, recognizing betamethasone’s impact on glucose metabolism helps understand the connection to hyperglycemia and its potential for causing complications in diabetic patients.